Vaccination: Epidemiological Review

Vaccination: Epidemiological Review

The induction of host protective immunity is an important factor in the immunization against potentially fatal disease and emerging illnesses in the U.S. and global populations especially among immunologically susceptible naïve hosts. Vaccination programs need to be evaluated as regards their health and economic population benefit among indigenous at risk populations taking into account emergin...

Epidemiological and Financial Implications of HPAI Vaccination

Epidemiological and evolutionary consequences of targeted vaccination.

Recent theory has examined the way in which vaccination strategies are expected to influence the evolution of parasite virulence. Most of this work has assumed that vaccination is imposed on a homogeneous host population. However, host populations are typically composed of different types of individuals, with each type responding differently to infection. Moreover, actual interventions often fo...

Imperfect vaccination: some epidemiological and evolutionary consequences.

An aim of some vaccination programmes is to reduce the prevalence of an infectious disease and ultimately to eradicate it. We show that eradication success depends on the type of vaccine as well as on the vaccination coverage. Vaccines that reduce the parasite within-host growth rate select for higher parasite virulence and this evolution may both increase the prevalence of the disease and prev...

Poliomyelitis: present epidemiological situation and vaccination problems.

In 1988 the World Health Organization (WHO) declared its commitment to the goal of global eradication of poliomyelitis by the year 2000, generating new enthusiasm in pursuing this objective worldwide. The nations involved are supported by a coalition of partners, including Rotary International, Centers for Disease Control and Prevention of Atlanta, Ga., UNICEF, and the WHO itself. Interventions...